Prenatal Diagnosis of β-thalassemia with Cell-free Fetal DNA in Maternal Plasma
نویسندگان
چکیده
منابع مشابه
Cell-free fetal DNA in maternal plasma and noninvasive prenatal diagnosis.
The noninvasive nature of the detection of fetal DNA in the maternal circulation represents the greatest advantage over the conventional methods of prenatal diagnosis. The applications of this methodology involve the detection of the fetal sex, and diagnosis, intra-uterine treatment, and evaluation of the prognosis of many diseases. Fetal cells detected in the maternal circulation have also bee...
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Since the existence of cell-free fetal DNA (cff-DNA) in maternal circulation was discovered, it has been identified as a promising source of fetal genetic material in the development of reliable methods for non-invasive prenatal diagnosis (NIPD) of fetal trisomy 21 (T21). Currently, a prenatal diagnosis of fetal T21 is achieved through invasive techniques, such as chorionic villus sampling or a...
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Objective: This study aimed to investigate the role of cell-free fetal DNA (cff-DNA) in the maternal plasma in the prenatal diagnosis of chromosomal abnormalities. Methods: The results of cell-free DNA detection of maternal plasma were retrospectively reviewed in 1440 pregnant women, and the pregnancy outcomes were followed up. Results: (1) Of 1440 pregnant women, 20 had a high risk for trisomy...
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In many farm animal species, the preference of a specific sex is obvious mainly due to commercial implications; so for comprehensive and efficient results in the livestock management plans specially breedingand selection programs, it is necessary to include acost-effective and reliable strategy for early determination of fetal sex. Several invasive and non-invasive approaches have been establis...
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context prenatal testing aims to identify fetal chromosomal and genetic disorders prior to delivery. current invasive procedures such as amniocentesis and chorionic villus sampling (cvs) pose a risk to mother and fetus and such diagnostic procedures are available only to high-risk pregnancies, which limits aneuploidy detection rate. the identification of cell-free fetal dna (cffdna) in maternal ...
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ژورنال
عنوان ژورنال: Journal of the College of Physicians and Surgeons Pakistan
سال: 2019
ISSN: 1022-386X,1681-7168
DOI: 10.29271/jcpsp.2019.05.483